Benefits of CBD —Supported by Science

Journal Back to Archive09.27.20

As we all know, CBD does not get you high. But recent studies and clinical trials have found various therapeutic benefits of taking CBD regularly. We list these below along with the relevant research. 

  1. Improves Mood
  2. Reduces Stress and Anxiety
  3. Relieves Pain
  4. Improves Sleep Quality
  5. Ease PMS Symptoms
  6. Reduces Inflammation
  7. Controls Auto-Immune Response. 
  8. Increases Libido and Quality of Orgasms
  9. Reduces Endometriosis Symptoms

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CBD Improves Mood

A study showed that CBD could replace antidepressants: CBD and imipramine were given to mice during a forced swimming test. Mice do not like to swim and so, naturally panic. The mice given CBD registered less stressful activity in their hippocampus (the area that controls our emotions) than those given anti-depressants.

 

This study shows how CBD can increase the serotonin levels in your brain: Serotonin is sometimes called a happy chemical because it contributes to wellbeing and happiness. 

 

This study showed CBD can reduce depression: A study on mice showed that after a seven-day treatment the mice had a decrease in anxiety-like behavior, and registered normalized 5-HT activity. The 5-HT receptor is linked to depression.

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CBD for Anxiety and Stress

A study showed that CBD could replace anxiety meds: CBD had a positive effect on the amygdala (fear center) and hippocampus (memory and emotion) areas of the limbic system —an effect that was considered comparable to the anxiety medications, ipsapirone, and diazepam. 

 

This study shows that CBD can help with public speaking: This study compared the effects of a simulation public speaking test (SPST) on healthy control (HC) patients and treatment-naïve SAD patients. Both subjects received a single dose of CBD or a placebo. It was found that CBD reduced the anxiety of those with SAD and they reported feeling the same healthy control patients. 

 

This study examines CBD as a Potential Treatment for Generalised Anxiety Disorders: This research found that existing preclinical evidence strongly supports CBD as a treatment for generalized anxiety disorder, panic disorder, social anxiety disorder, obsessive-compulsive disorder, and post-traumatic stress disorder when administered acutely.

 

This study examines if CBD could be an Adjunctive Therapy in Schizophrenia: The findings suggest that CBD has beneficial effects in patients with schizophrenia. As CBD’s effects do not appear to depend on dopamine receptor antagonism, this agent may represent a new class of treatment for the disorder.

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CBD for Pain

This study shows that CBD is effective in the management of difficult to treat pain: This breaks down the clinical trials that led to Sativex, a Cannabinoid drug to be approved in Canada. In particular for the treatment of central and peripheral neuropathic pain (MS), rheumatoid arthritis, and cancer pain. 

A second study is here

 

This study shows that CBD regulates nerve growth and their receptors: Using clinical trials it was shown that endocannabinoids help regulate nerve growth and their receptors. They can desensitize our nerves, by preventing the nerve receptors from being turned on, so we do not get the message to our brain about the pain.⁠

A second study proving CBD is a powerful analgesic is here.

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CBD for Sleep Quality

This study compared if CBD could be better than sleep aid nabilone: It demonstrated that CBD may hold promise for REM sleep behavior disorder and excessive daytime sleepiness, while nabilone may reduce nightmares associated with PTSD and may improve sleep among patients with chronic pain.

 

This study showed CBD proved 72% effective for people with anxiety-related sleep disturbance: CBD was given to 102 patients in a psychiatric clinic. And it was reported that sleep scores improved within the first month in 48 patients (66.7%).

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CBD for PMS Symptoms

There is minimal research examining the link between cannabinoids and female hormones. So, instead, we need to examine the studies that show how CBD can treat the symptoms of PMS 

—And it has been proven that CBD can help relax the uterine muscle where cramps occur, decrease inflammation and pain in our body, and help with anxiety, mood swings, and irritability during our period. 

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CBD for Inflammation

This study shows that CBD can have Antioxidative and Anti-Inflammatory Properties: It has been proven that your ECS can prevent the body’s inflammatory response when stimulated with additional Phytocannabinoids, like CBD.

Further study is here

 

This study looked at the Antioxidative and Anti-Inflammatory Properties of Cannabidiol: The research examines clinical trials where CBD has been shown to suppress T-cell-mediated immune responses. In cases where the T-cell response is actually overactive and degenerative to the body. Regulating T-cells response is critical to the regulation and mediation of inflammatory or autoimmune disease response.

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CBD for Autoimmune disease

This study shows that CBD is an excellent treatment for MS and other autoimmune diseases: 20 mg/kg body weight of CBD or placebo was administered to patients with MS and Huntington’s disease in a clinical trial. And it was found that CBD is able to target a range of anti-inflammatory pathways, including (i) induction of anti-inflammatory MDSCs and (ii) decrease in pro-inflammatory and induction of anti-inflammatory cytokines.

 

This study shows that CBD can reduce the neurodegenerative effects associated with auto-immune disease. 

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CBD Increases Libido and Quality of Orgasms

This study shows that CBD can increase secretion of ‘Cuddle hormone’: The research testifies that CBD increases the serum concentration of an endocannabinoid neurotransmitter called anandamide. Anandamide is very closely related to the hormone oxytocin, commonly known as the cuddle hormone. This can provide for a deeper emotional connection during intimacy.

 

This study shows that CBD can increase your desire for intimacy: Mice were given CBD during social bonding exercises, and it was found that their desire for intimacy was increased, this was from an increased release of anandamide. They were also more inclined to repeat these behaviors afterward. We can draw the conclusion that an increase in anandamide, induced by CBD, increases the pleasure you get from that connection. 

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CBD for Endometriosis

The most promising study shows that modulation of the ECS through therapeutic doses of CBD could be the key to real endometriosis treatment. This study shows a link between the systems maintained by the ECS and our body’s endometrial cells. And draws the conclusion that if we regulate our ECS we could actually treat and maybe cure endometriosis.

A second study out of the UK studied the link between our *ECS and endometriosis. The research showed that women without endometriosis had well functioning CB1 and CB2 receptors. But, women with endometriosis had very sluggish ones. Our ECS system needs cannabinoids to keep it functioning effectively. Thus, perhaps daily cannabinoids could help women with endometriosis combat the disorder.

CBD CAN reduce THE BRAIN FOG ASSOCIATED WITH ENDOMETRIOSIS

A recent study showed that Cannabinoids can improve endometriosis symptoms in mice. It showed that those mice who had endo experienced anxiety and pain which affected their cognitive function. But when given cannabinoids their cognitive function improved, drawing the hypothesis that their anxiety and pain from the endo was the cause of their brain fog.

CBD COULD HELP THE BODY DESTROY THE ‘ALIEN; ENDOMETRIAL CELLS AND PREVENT THEM FROM SPREADING.

It is also widely accepted that endometrial cells behave in the same way as cancer cells, BUT BENIGN. So when referencing other studies that prove phtyo-cannabinoids could help endometriosis we can reference cancer + Cannabis studies. This study shows cannabinoids stop tumor cells from growing in mice. Mice given cannabinoids were able to destroy alien cells in their bodies. Endometrial cells growing outside your uterus are ‘alien’ cells. Potentially if you feed an endo patient the phytocannabinoid CBD their body will begin to destroy these alien cells. This has also been proven here and here.

CBD IS AN EFFECTIVE ANALGESIC AND stops PAIN.

Often the collection of endo cells can develop a very rich population of nerve endings, causing serious pain. Studies have shown that endocannabinoids help regulate nerve growth and their receptors —CBD can desensitize our nerves, by preventing the nerve receptors from being turned on, so we do not get the message to our brain about the pain. More here and here.

CBD CAN COMBAT THE AUTO-IMMUNE ISSUES YOU CAN GET FROM ENDOMETRIOSIS BY DECREASING INFLAMMATION.

When you have endo your body is confused and can start to attack all the cells in your body, as it does not know what to do with the dead cells. Studies show your ECS can prevent the body’s inflammatory response when stimulated with additional Phytocannabinoids, like CBD. Another study shows how CBD can also reduce the body’s T-cells proliferation, and is a promising treatment of auto-immune disease.